Levocarnitine

Levocarnitine

SCHEMBL4593172

C[N+](C)(C)C[C@H](O)CC(=O)[O-].C[N+](C)(C)C[C@H](O)CC(=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A16 Q86VW1 1/20 1.00
CPT2 P23786 2/20 0.61
CPT1A P50416 2/20 0.61
MAPT P10636 2/20 0.60
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
CYP1A2 P05177 1/20 0.53
HRH1 P35367 1/20 0.53
CRAT P43155 1/20 0.53
CYP2C19 P33261 2/20 0.50
RECQL P46063 1/20 0.50
CA4 P22748 2/20 0.44
CA2 P00918 1/20 0.44
SLC25A20 O43772 3/20 0.42
TP53 P04637 2/20 0.42
CYP2D6 P10635 2/20 0.42
TSHR P16473 2/20 0.42
CPT1B Q92523 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carnitine SCHEMBL21971 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL17629811 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Levocarnitine SCHEMBL21970 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL1813524 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL3902633 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
D-Carnitine SCHEMBL94286 1.00 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Levocarnitine SCHEMBL23249739 0.98 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL1456305 0.98 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL357560 0.98 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL8389713 0.98 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101317817-A External slimming coating agent ZHONGHUA YUAN (CN) 2008-12-10 CN claimed
EP-3675838-A1 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS Puretecch LYT, Inc. (US) 2020-07-08 EP disclosed
WO-2019046491-A1 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS ARIYA THERAPEUTICS, INC. (US) 2019-03-07 WO disclosed
CN-1895671-B Compound preparation for treating viral liver disease HUIKE PHARMACEUTICAL CO LTD HUAIBEI 2012-11-28 CN disclosed
CN-101317817-A External slimming coating agent ZHONGHUA YUAN (CN) 2008-12-10 CN disclosed
WO-2008054695-A2 COMPOSITION AND METHOD FOR ETIOLOGICAL TREATMENT AND PREVENTION OF DISEASES AND/OR COMPLICATIONS ASSOCIATED WITH CHRONIC GLUCOSE METABOLISM DESTABILIZATION GUFFEY MANNING V (US) 2008-05-08 WO disclosed
EP-1901715-A2 SPRAY-DRYING PROCESS FOR PRODUCING A DRY CARNITINE POWDER OR GRANULATE LONZA AG (CH) 2008-03-26 EP disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed
CN-1895671-A Compound preparation for treating viral liver disease HUIKE PHARMACEUTICAL CO LTD HU (CN) 2007-01-17 CN disclosed
WO-2007003425-A2 SPRAY-DRYING PROCESS FOR PRODUCING A DRY CARNITINE POWDER OR GRANULATE LONZA AG (CH) 2007-01-11 WO disclosed
US-5238838-A Hydrolysis catalysts converting L-carnitine amide to L-carnitine; stereospecific DEGUSSA AKTIENGESELLSCHAFT (DE) 1993-08-24 US disclosed
US-4362719-A INSULIN, MIXTURES CAVAZZA CLAUDIO 1982-12-07 US disclosed