Carnitine

Carnitine

SCHEMBL357560

C[N+](C)(C)CC(O)CC(=O)[O-].Cl

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Carnitine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 known ✓ P35367 1/20 0.52
CA2 known ✓ P00918 1/20 0.42
SLC22A16 Q86VW1 1/20 0.95
CPT2 P23786 2/20 0.59
CPT1A P50416 2/20 0.59
MAPT P10636 2/20 0.58
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CYP1A2 P05177 1/20 0.52
CRAT P43155 1/20 0.52
CYP2C19 P33261 2/20 0.48
RECQL P46063 1/20 0.48
CA4 P22748 2/20 0.42
SLC25A20 O43772 3/20 0.41
TP53 P04637 2/20 0.41
CYP2D6 P10635 2/20 0.41
TSHR P16473 2/20 0.41
CPT1B Q92523 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Carnitine SCHEMBL6855781 1.00 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Levocarnitine SCHEMBL388330 1.00 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Levocarnitine SCHEMBL9633322 1.00 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL10631240 1.00 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL10435820 1.00 SLC22A16 (0.95) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL10633747 0.98 SLC22A16 (0.91) SLC22A16CPT2CPT1AMAPTMEN1
Levocarnitine SCHEMBL21970 0.98 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
D-Carnitine SCHEMBL94286 0.98 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL21971 0.98 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1
Carnitine SCHEMBL1813524 0.98 SLC22A16 (1.00) SLC22A16CPT2CPT1AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204609-B1 COMPOSITIONS AND METHODS FOR THE ELECTRODEPOSITION OF NANOTWINNED COPPER MACDERMID ENTHONE INC (US) 2026-05-27 EP claimed
CN-122005509-A High-efficiency absorption ergothioneine orosol film and preparation method thereof 上海欣峰健康科技有限公司 2026-05-12 CN claimed
US-12600953-B2 Compositions and method for establishing organoid cultures from cryogenically preserved tissue THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-04-14 US claimed
US-20260078517-A1 COMPOSITION AND METHOD FOR NANOTWINNED COPPER FORMATION MACDERMID ENTHONE INC (US) 2026-03-19 US claimed
CN-121583971-A Application of carnitine hydrochloride in zinc-bromine flow battery electrolyte, zinc-bromine flow battery electrolyte and battery 北京化工大学 2026-02-27 CN claimed
EP-4687485-A1 NOVEL COMBINATIONS COMPRISING KONJAC MANNAN, THEIR COMPOSITIONS AND USES THEREOF Vivatis Pharma GmbH (DE) 2026-02-11 EP claimed
EP-4687486-A1 NOVEL COMBINATIONS COMPRISING KONJAC MANNAN, THEIR COMPOSITIONS AND USES THEREOF Vivatis Pharma GmbH (DE) 2026-02-11 EP claimed
US-20260000673-A1 BRAIN HEALTH SUPPLEMENT MAGOOLA MATTHIAS (UG) 2026-01-01 US claimed
US-12378529-B2 Method for culturing colorectal cancer solid tumor primary cells and colorectal cancer ascites primary tumor cells and supporting reagents GENEX HEALTH CO., LTD (CN) 2025-08-05 US claimed
CN-222980273-U High-power high-frequency inductor with auxiliary heat dissipation function 江西省高新超越精密电子有限公司 2025-06-13 CN claimed
US-5158770-A Mixture of organic solvent, alcohol, and nitrogen containing compound FREUND INDUSTRIAL CO., LTD. (JP) 1992-10-27 US claimed
EP-0416583-A1 Method for the preparation of crotonobetaine hydrochloride LONZA AG (CH) 1991-03-13 EP claimed
US-4933490-A Process for the preparation of L(-)carnitine hydrochloride and of L(-)carnitine inner salt ISOM S.P.A. (IT) 1990-06-12 US claimed
EP-0141408-B1 PROCESS FOR THE PREPARATION OF L(-)CARNITINE HYDROCHLORIDE AND OF L(-)CARNITINE INNER SALT ISOM S.p.A. (IT) 1989-08-23 EP claimed
EP-0207437-B1 NEW CARNITINE SALTS PARTICULARLY SUITABLE FOR ORAL USE BIORESEARCH S.p.A. (IT) 1988-08-24 EP claimed
US-4673534-A ALKYLSULFONATE SALTS, USEFUL IN TREATMENT OF MYOPATHY BIORESEARCH SPA (IT) 1987-06-16 US claimed
EP-0207437-A1 New Carnitine salts particularly suitable for oral use BIORESEARCH S.p.A. (IT) 1987-01-07 EP claimed
US-4021480-A Process for the production of carnitine LONZA LTD. (CH) 1977-05-03 US claimed
US-4018821-A Process for the production of carnitine LONZA LTD. (CH) 1977-04-19 US claimed
US-3969406-A Process for the production of carnitine LONZA LTD. (CH) 1976-07-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600953-B2 Compositions and method for establishing organoid cultures from cryogenically preserved tissue BMP4, DSP, WNT3A HRH1 3329/4885CA2 1828/4885SLC22A16 4303/4885
US-20260078517-A1 COMPOSITION AND METHOD FOR NANOTWINNED COPPER FORMATION AOC2, HCN2, STMN2 HRH1 1503/4885CA2 1519/4885SLC22A16 1595/4885
US-20260000673-A1 BRAIN HEALTH SUPPLEMENT SNCA, SLC19A2, FABP2 HRH1 865/4885CA2 3354/4885SLC22A16 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.