Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593400 | 0.89 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL4080325 | 0.86 | TLR8 (0.54) | TLR8TLR7NUDT1 | |
| SCHEMBL3867005 | 0.83 | TLR8 (0.52) | TLR8TLR7NUDT1 | |
| SCHEMBL12003054 | 0.83 | TLR8 (0.68) | TLR8TLR7NUDT1 | |
| SCHEMBL3864546 | 0.82 | TLR7 (0.54) | TLR8TLR7NUDT1 | |
| SCHEMBL12756930 | 0.80 | TLR7 (0.57) | TLR8TLR7NUDT1 | |
| SCHEMBL1960130 | 0.80 | TLR7 (0.70) | TLR8TLR7 | |
| SCHEMBL1490824 | 0.79 | TLR7 (0.53) | TLR8TLR7NUDT1 | |
| SCHEMBL29034534 | 0.79 | TLR7 (0.71) | TLR8TLR7 | |
| SCHEMBL6722353 | 0.78 | TLR8 (0.66) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685129-A4 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1685129-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005048933-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |