Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594971 | 0.92 | SSTR5 (0.34) | SSTR5KCNH2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4594457 | 0.89 | SSTR5 (0.39) | SSTR5KCNH2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4594469 | 0.89 | SSTR5 (0.36) | SSTR5KCNH2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4594414 | 0.89 | SSTR5 (0.37) | SSTR5KCNH2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4594337 | 0.88 | SSTR5 (0.40) | SSTR5KCNH2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4594514 | 0.87 | SSTR5 (0.46) | SSTR5KCNH2ALOX5APFEN1 | |
| SCHEMBL4593756 | 0.87 | SSTR5 (0.47) | SSTR5KCNH2ALDH1A1SMN1; SMN2ALOX5AP | |
| SCHEMBL5486981 | 0.85 | SSTR5 (0.37) | SSTR5KCNH2ALDH1A1HTTHTR2A | |
| SCHEMBL4594200 | 0.85 | SSTR5 (0.37) | SSTR5KCNH2ALDH1A1HTTHTR2A | |
| SCHEMBL4593242 | 0.85 | EP300 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |