Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593279 | 0.89 | MAPT (0.35) | EP300 | |
| SCHEMBL4593717 | 0.85 | SSTR5 (0.39) | EP300 | |
| SCHEMBL4593433 | 0.85 | SSTR5 (0.37) | — | |
| SCHEMBL4594971 | 0.85 | SSTR5 (0.34) | — | |
| SCHEMBL4594414 | 0.82 | SSTR5 (0.37) | — | |
| SCHEMBL4594457 | 0.82 | SSTR5 (0.39) | — | |
| SCHEMBL4594469 | 0.82 | SSTR5 (0.36) | — | |
| SCHEMBL4594337 | 0.81 | SSTR5 (0.40) | — | |
| SCHEMBL4594247 | 0.75 | SSTR5 (0.39) | — | |
| SCHEMBL4594274 | 0.74 | REN (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |