Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780411 | 0.86 | CALCRL (0.67) | CALCRLCYP3A4 | |
| SCHEMBL3598516 | 0.85 | CALCRL (1.00) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL4504325 | 0.80 | CALCRL (1.00) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL3598277 | 0.77 | CALCRL (0.82) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL4720735 | 0.77 | CALCRL (0.55) | CALCRL | |
| SCHEMBL4507434 | 0.77 | CALCRL (0.64) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL4517575 | 0.77 | CALCRL (0.75) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL13756214 | 0.77 | CALCRL (0.81) | CALCRLCYP3A4CYP2D6 | |
| SCHEMBL30231296 | 0.76 | CALCRL (1.00) | CALCRLCYP3A4 | |
| SCHEMBL3607210 | 0.76 | CALCRL (1.00) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689493-A4 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2008-04-23 | — | — | EP | claimed |
| EP-1689493-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Pharma Company (US) | 2006-08-16 | — | — | EP | claimed |
| WO-2005065779-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-21 | — | — | WO | claimed |
| EP-1689493-A4 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1689493-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Pharma Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005065779-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |