Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801125 | 0.88 | PIP4K2C (0.38) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3798041 | 0.83 | LMNA (0.44) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3802402 | 0.80 | LMNA (0.47) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3798486 | 0.79 | LMNA (0.47) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3799687 | 0.72 | PIP4K2C (0.52) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3798672 | 0.71 | NPC1 (0.41) | LMNARAB9APIP4K2CFLT3CDK2 | |
| SCHEMBL3802570 | 0.70 | PIP4K2C (0.53) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3810827 | 0.70 | HTT (0.51) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3799470 | 0.70 | PIP4K2C (0.52) | LMNARAB9ARXFP1NOD2PIP4K2C | |
| SCHEMBL3797949 | 0.70 | MRGPRX1 (0.50) | LMNARAB9ARXFP1NOD2PIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059905-A9 | THIENOPYRIMIDINES TREATING INFLAMMATORY DISEASES | DEVELOGEN AG (DE) | 2007-11-01 | — | — | WO | claimed |
| WO-2007059905-A2 | THIENOPYRIMIDINES TREATING INFLAMMATORY DISEASES | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2007-05-31 | — | — | WO | claimed |
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |