Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | PDE4A | P27815 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858437 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL3234167 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL5494252 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL6684344 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL3245395 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL5497371 | 0.97 | MEN1 (0.74) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL4307435 | 0.93 | MEN1 (0.84) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL5426502 | 0.93 | MEN1 (0.84) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL7440528 | 0.93 | MEN1 (0.69) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL3244539 | 0.93 | MEN1 (0.84) | MEN1CHRM1PDE4AKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567161-A4 | PHARMACEUTICAL COMPOSITION OF 1-(3,4-DIMETHOXYPHENYL)-4-METHYL-5-ETHYL-7-METHOXY-8-HYDROXY-5H-2,3-BENZODIAZEPINE AND USES THEREOF | VELA ACQUISITION CORP (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1567161-A2 | PHARMACEUTICAL COMPOSITION OF 1-(3,4-DIMETHOXYPHENYL)-4-METHYL-5-ETHYL-7-METHOXY-8-HYDROXY-5H-2,3-BENZODIAZEPINE AND USES THEREOF | Vela Pharmaceuticals Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050040-A2 | PHARMACEUTICAL COMPOSITION OF 1-(3,4-DIMETHOXYPHENYL)-4-METHYL-5-ETHYL-7-METHOXY-8-HYDROXY-5H-2,3-BENZODIAZEPINE AND USES THEREOF | VELA PHARMACEUTICALS, INC. (US) | 2004-06-17 | — | — | WO | disclosed |