Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | RAC1 | P63000 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497371 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL6684344 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3245395 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5494252 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL6858437 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL3234167 | 0.94 | MEN1 (0.74) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL4593681 | 0.93 | MEN1 (0.73) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7432334 | 0.92 | MEN1 (0.70) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5426502 | 0.91 | MEN1 (0.84) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL4307435 | 0.91 | MEN1 (0.84) | MEN1KMT2ACHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548370-A1 | DRUG FOR PREVENTING AND/OR TREATING ALLERGIC DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |