Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024822 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4594508 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024959 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL7431853 | 0.77 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRHSD17B10RECQL | |
| SCHEMBL19024941 | 0.77 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024870 | 0.77 | PRSS1 (0.51) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024961 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL27728355 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024630 | 0.75 | PRSS1 (0.52) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024839 | 0.75 | PRSS1 (0.52) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871339-A1 | UV PROTECTION | Merck Patent GmbH (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111234-A1 | UV PROTECTION | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |