Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585902 | 0.94 | KDR (0.45) | KDRITK | |
| SCHEMBL4594057 | 0.83 | KDR (0.49) | KDRITK | |
| SCHEMBL4593040 | 0.80 | KDR (0.41) | KDRITK | |
| SCHEMBL4593037 | 0.80 | KDR (0.41) | KDRITK | |
| SCHEMBL4587497 | 0.78 | KDR (0.43) | KDR | |
| SCHEMBL4594715 | 0.78 | KDR (0.43) | KDR | |
| SCHEMBL7003815 | 0.76 | KDR (0.55) | KDR | |
| SCHEMBL4594092 | 0.74 | NSD2 (0.49) | KDR | |
| SCHEMBL4594178 | 0.74 | KDR (0.52) | KDR | |
| SCHEMBL4592543 | 0.73 | KDR (0.60) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558609-A4 | KINASE INHIBITORS | MERCK & CO INC (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1558609-A2 | KINASE INHIBITORS | Merck & Co., Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004041164-A2 | KINASE INHIBITORS | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | disclosed |