Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593766 | 1.00 | FDPS (0.48) | FDPSACHEBCHEMAPTHPGD | |
| SCHEMBL4593767 | 0.84 | FDPS (0.57) | FDPSACHEBCHEMAPTHPGD | |
| SCHEMBL4593774 | 0.84 | FDPS (0.57) | FDPSACHEBCHEMAPTHPGD | |
| SCHEMBL2639472 | 0.75 | FDPS (0.85) | FDPSACHEBCHEMAPTALDH1A1 | |
| SCHEMBL2639470 | 0.75 | FDPS (0.85) | FDPSACHEBCHEMAPTALDH1A1 | |
| SCHEMBL28386773 | 0.73 | FDPS (0.71) | FDPSACHEBCHEMAPTALDH1A1 | |
| SCHEMBL5173870 | 0.73 | FDPS (0.56) | FDPSACHEBCHEMAPTHPGD | |
| SCHEMBL18270975 | 0.73 | FDPS (0.75) | FDPSACHEBCHEMAPTHPGD | |
| SCHEMBL7336967 | 0.72 | APP (0.55) | FDPSKDM4ESMN1; SMN2APP | |
| SCHEMBL12279445 | 0.72 | APP (0.55) | FDPSKDM4ESMN1; SMN2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187802-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2008-01-02 | — | — | EP | disclosed |
| EP-1187802-A1 | LIQUID CRYSTAL COMPOUNDS | Rolic AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000063154-A1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2000-10-26 | — | — | WO | disclosed |
| EP-1046631-A1 | Liquid crystalline compounds | Rolic AG (CH) | 2000-10-25 | — | — | EP | disclosed |