Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 18/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594371 | 0.93 | SSTR5 (0.46) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4594246 | 0.88 | NPC1 (0.44) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4594394 | 0.88 | SSTR1 (0.39) | SSTR5SSTR1HDAC6 | |
| SCHEMBL4593325 | 0.87 | SSTR5 (0.46) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4593786 | 0.84 | SSTR5 (0.35) | SSTR5KCNH2 | |
| SCHEMBL4594240 | 0.84 | SSTR5 (0.36) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4594383 | 0.84 | SSTR5 (0.42) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4594097 | 0.82 | SSTR5 (0.48) | SSTR5KCNH2SSTR1 | |
| SCHEMBL3978900 | 0.80 | SSTR5 (0.44) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4593898 | 0.80 | SSTR5 (0.45) | SSTR5SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |