Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 16/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594459 | 0.91 | SSTR5 (0.35) | SSTR5KCNH2IKBKBSLC6A2SLC6A4 | |
| SCHEMBL4594470 | 0.90 | SSTR5 (0.36) | SSTR5KCNH2SSTR3SSTR1SLC6A2 | |
| SCHEMBL4593240 | 0.90 | SSTR5 (0.36) | SSTR5KCNH2SSTR3SSTR1SLC6A2 | |
| SCHEMBL4594449 | 0.88 | SSTR5 (0.36) | SSTR5KCNH2SSTR3SSTR1SLC6A2 | |
| SCHEMBL4594219 | 0.88 | SSTR5 (0.36) | SSTR5KCNH2SSTR1IKBKBSLC6A2 | |
| SCHEMBL4594815 | 0.87 | NPC1 (0.40) | SSTR5KCNH2SSTR3SSTR1 | |
| SCHEMBL4593376 | 0.87 | SSTR5 (0.36) | SSTR5KCNH2SSTR3SSTR1SLC6A2 | |
| SCHEMBL4594566 | 0.86 | HTR2A (0.35) | SSTR5KCNH2SSTR3SSTR1 | |
| SCHEMBL4593265 | 0.85 | SSTR5 (0.40) | SSTR5KCNH2SSTR3SSTR1SLC6A2 | |
| SCHEMBL4594753 | 0.84 | MAPT (0.37) | SSTR5KCNH2SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |