SCHEMBL4594058

SCHEMBL4594058

CCCCCCCCCCCCN1CCC(CC)C1(CC)CC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 8/20 0.41
GNAI3 P08754 7/20 0.41
GNAI1 P63096 7/20 0.41
BCHE P06276 5/20 0.35
GBA1 P04062 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13902630 0.79 GNAO1 (0.46) GNAO1GNAI3GNAI1BCHEGBA1
SCHEMBL13681801 0.68 GNAO1 (0.45) GNAO1GNAI3GNAI1BCHEGBA1
SCHEMBL27398041 0.64 GNAO1 (0.63) GNAO1GNAI3GNAI1KCNH2
SCHEMBL7741626 0.64 GNAO1 (0.63) GNAO1GNAI3GNAI1KCNH2
Hydrochloric Acid SCHEMBL30330839 0.63 GNAO1 (0.67) GNAO1GNAI3GNAI1KCNH2
Fluoride SCHEMBL29252160 0.63 GNAO1 (0.61) GNAO1GNAI3GNAI1KCNH2
Hydrochloric Acid SCHEMBL29252120 0.63 GNAO1 (0.67) GNAO1GNAI3GNAI1KCNH2
Fluoride SCHEMBL29252550 0.63 GNAO1 (0.61) GNAO1GNAI3GNAI1KCNH2
Fluoride SCHEMBL29252378 0.63 GNAO1 (0.61) GNAO1GNAI3GNAI1KCNH2
Hydrochloric Acid SCHEMBL30330488 0.63 GNAO1 (0.67) GNAO1GNAI3GNAI1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1613573-A4 PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID DU PONT (US) 2008-10-29 EP disclosed
EP-1613573-A2 PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-01-11 EP disclosed
WO-2004085349-A2 PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-10-07 WO disclosed