SCHEMBL45941

SCHEMBL45941

N#CC1CCC(C#N)CC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6618 1.00
SCHEMBL1343696 1.00 KDM4E (0.34) KDM4EALDH1A1CA1CA2
SCHEMBL1164553 1.00 KDM4E (0.34) KDM4EALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL1200019 0.96
SCHEMBL28386367 0.96
Ammonia Solution, Strong SCHEMBL16007514 0.96
Hydrochloric Acid SCHEMBL5048648 0.92
SCHEMBL820230 0.89 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL820635 0.89 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL2154068 0.89 KDM4E (0.31) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778544-B1 PRODUCTION METHOD FOR 1,4-CYCLOHEXANEDICARBOXYLIC ACID DERIVATIVE, 1,4-DICYANOCYCLOHEXANE AND 1,4-BIS(AMINOMETHYL)CYCLOHEXANE MITSUBISHI GAS CHEMICAL CO (JP) 2026-05-20 EP claimed
CN-111886217-B Process for producing cyclohexanedicarboxylic acid, dicyanocyclohexane and bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2024-09-13 CN claimed
CN-117673467-A Electrolyte and battery comprising same 珠海冠宇电池股份有限公司 2024-03-08 CN claimed
CN-117003655-A Synthesis method of tranexamic acid 上海巽田科技股份有限公司 2023-11-07 CN claimed
CN-116947663-A Synthesis method of tranexamic acid 上海巽田科技股份有限公司 2023-10-27 CN claimed
CN-111954656-B Process for producing 1, 4-cyclohexanedicarboxylic acid derivative, 1, 4-dicyanocyclohexane and 1, 4-bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2023-08-01 CN claimed
US-11472765-B2 Production method for 1,4-cyclohexanedicarboxylic acid derivative, 1,4-dicyanocyclohexane and 1,4-bis(aminomethyl)cyclohexane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-10-18 US claimed
CN-109641833-B Process for producing 1, 4-dicyanocyclohexane, 1, 4-bis (aminomethyl) cyclohexane and 1, 4-cyclohexanedicarboxylic acid 三菱瓦斯化学株式会社 2022-02-22 CN claimed
EP-3524590-B1 METHOD FOR PRODUCING 1, 4-DICYANOCYCLOHEXANE, 1, 4-BIS(AMINOMETHYL)CYCLOHEXANE AND 1, 4-CYCLOHEXANEDICARBOXYLIC ACID MITSUBISHI GAS CHEMICAL CO (JP) 2021-10-27 EP claimed
CN-109956887-B Method for preparing 1, 4-cyclohexanedicarbonitrile by catalyzing ammoxidation and cracking of 1, 4-cyclohexanedimethanol 中国科学院大连化学物理研究所 2021-06-01 CN claimed
WO-2007145981-A1 PROCESS FOR THE DIRECT SYNTHESIS OF TRIALKOXYSILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-12-21 WO claimed
US-20070287850-A1 Process for the direct synthesis of trialkoxysilane MOMENTIVE PERFORMANCE MATERIALS INC. 2007-12-13 US claimed
EP-1246794-A4 PROCESS AND INTERMEDIATES FOR PREPARING A CYCLOHEXYLNITRILE SMITHKLINE BEECHAM CORP (US) 2005-10-05 EP claimed
EP-1246794-A1 PROCESS AND INTERMEDIATES FOR PREPARING A CYCLOHEXYLNITRILE SmithKline Beecham Corporation (US) 2002-10-09 EP claimed
WO-2001051455-A1 PROCESS AND INTERMEDIATES FOR PREPARING A CYCLOHEXYLNITRILE SMITHKLINE BEECHAM CORPORATION (US) 2001-07-19 WO claimed
US-6005118-A Methods of preparing 4-cyano-4 (substituted indazole) cyclohexane-carboxylic acids useful as PDE4 inhibitors PFIZER INC. 1999-12-21 US claimed
EP-0915089-A2 Methods of preparing 4-cyano-4-(substituted indazole)cyclohexane-carboxylic acids useful as PDE4 inhibitors Pfizer Products Inc. (US) 1999-05-12 EP claimed
US-5874625-A Process to hydrogenate organic nitriles to primary amines HENKEL CORPORATION (US) 1999-02-23 US claimed
WO-1998019991-A1 IMPROVED PROCESS TO HYDROGENATE ORGANIC NITRILES TO PRIMARY AMINES HENKEL CORPORATION (US) 1998-05-14 WO claimed
US-4007226-A TO FORM AMINES, COBALT OXIDE-SODIUM SILICATE CATALYST EASTMAN KODAK COMPANY (US) 1977-02-08 US claimed