⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343696 | 1.00 | KDM4E (0.34) | — | |
| SCHEMBL1164553 | 1.00 | KDM4E (0.34) | — | |
| SCHEMBL45941 | 1.00 | KDM4E (0.34) | — | |
| Hydrochloric Acid SCHEMBL1200019 | 0.96 | — | — | |
| SCHEMBL28386367 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL16007514 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL5048648 | 0.92 | — | — | |
| SCHEMBL820230 | 0.89 | KDM4E (0.31) | — | |
| SCHEMBL820635 | 0.89 | KDM4E (0.31) | — | |
| SCHEMBL2154068 | 0.89 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5885 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372916-B1 | — | — | None | — | — | US | claimed |
| EP-4746963-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | claimed |
| CN-122071459-A | Heterocyclic derivative containing oxazole or salt acceptable as pesticide, composition and application thereof | 沈阳禧沅峰生物科技有限公司 | 2026-05-22 | — | — | CN | claimed |
| EP-4041730-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2026-05-13 | — | — | EP | claimed |
| EP-3856179-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-13 | — | — | EP | claimed |
| EP-4076459-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-04-29 | — | — | EP | claimed |
| EP-4142874-B1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2026-04-22 | — | — | EP | claimed |
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | claimed |
| US-12540131-B2 | N-(heteroaryl) quinazolin-2-amine derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-02-03 | — | — | US | claimed |
| EP-4436667-B1 | PIPERAZINYLSULFONYLARYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2026-01-21 | — | — | EP | claimed |
| EP-0296749-A1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LIMITED (GB) | 1988-12-28 | — | — | EP | claimed |
| EP-0070608-B1 | PHOTOISOMERISATION OF TRANS-CYCLOPROPANE-NITRILES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-01-16 | — | — | EP | claimed |
| US-4421618-A | CONVERSION TO CIS ISOMER | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B. V. (NL) | 1983-12-20 | — | — | US | claimed |
| EP-0070608-A1 | Photoisomerisation of trans-cyclopropane-nitriles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-01-26 | — | — | EP | claimed |
| EP-0002077-B1 | ESTERS OF SUBSTITUTED CYCLOPROPANECARBOXYLIC ACIDS AND PROCESS FOR THE PREPARATION THEREOF | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-09-02 | — | — | EP | claimed |
| US-4236018-A | Process for preparing cyclopropane carboxylic acids | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-11-25 | — | — | US | claimed |
| US-4205009-A | USING ANIONIC SURFACTANT | VELSICOL CHEMICAL CORPORATION (US) | 1980-05-27 | — | — | US | claimed |
| US-4174348-A | Preparation of cyclopropanecarbonitriles | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B. V. (NL) | 1979-11-13 | — | — | US | claimed |
| EP-0002077-A1 | Esters of substituted cyclopropanecarboxylic acids and process for the preparation thereof | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-05-30 | — | — | EP | claimed |
| US-3974199-A | Process for production of cyclopropylcyanide | THE DOW CHEMICAL COMPANY (US) | 1976-08-10 | — | — | US | claimed |