Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | PREP | P48147 | 6/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830113 | 1.00 | HRH3 (0.48) | HRH3DPP4PREPPDE8BTP53 | |
| SCHEMBL4593356 | 0.92 | TSHR (0.47) | TP53ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL6827794 | 0.90 | TP53 (0.49) | TP53LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL6828516 | 0.88 | ALDH1A1 (0.49) | DPP4PREPTP53ALDH1A1LMNA | |
| SCHEMBL6825229 | 0.87 | PPARA (0.43) | DPP4PREPTP53SMN1; SMN2MAPT | |
| SCHEMBL197391 | 0.83 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL875490 | 0.83 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL6828173 | 0.83 | DPP4 (0.44) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL4593481 | 0.83 | DPP4 (0.44) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL6827791 | 0.82 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917001-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007017423-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |