SCHEMBL4594385

SCHEMBL4594385

CC(C)=NOCc1nc2c(N)nc3cccnc3c2n1CCCN(C(N)=O)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1490870 0.89 TLR7 (0.37) TLR7
SCHEMBL1490827 0.84 TLR7 (0.36) TLR7
SCHEMBL7142636 0.83 TLR7 (0.48) TLR7
SCHEMBL1490706 0.82 CNR1 (0.37) TLR7
SCHEMBL1490342 0.81 F2 (0.33)
SCHEMBL1490794 0.79 TLR7 (0.41) TLR7
SCHEMBL1490740 0.77 TLR7 (0.38) TLR7
SCHEMBL1490322 0.76 TLR7 (0.47) TLR7
SCHEMBL1490762 0.74 CXCR3 (0.37) TLR7
SCHEMBL1490443 0.74 TLR7 (0.44) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1685129-A4 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2008-10-22 EP disclosed
EP-1685129-A2 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M Innovative Properties Company (US) 2006-08-02 EP disclosed
WO-2005048933-A2 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-02 WO disclosed