Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL2145949 | 0.82 | — | — | |
| Dimethylformamide SCHEMBL6607493 | 0.81 | TSHR (0.53) | TSHR | |
| Dimethylformamide SCHEMBL2184966 | 0.81 | TSHR (0.53) | TSHR | |
| Dimethylformamide SCHEMBL124684 | 0.81 | TSHR (0.53) | TSHR | |
| Dimethylformamide SCHEMBL2184967 | 0.79 | TSHR (0.50) | TSHR | |
| Dimethylformamide SCHEMBL28224916 | 0.79 | — | — | |
| Dimethylformamide SCHEMBL27730194 | 0.79 | TSHR (0.69) | TSHR | |
| Dimethylformamide SCHEMBL1927321 | 0.78 | TSHR (1.00) | TSHR | |
| Dimethylformamide SCHEMBL10141201 | 0.78 | — | — | |
| Dimethylformamide SCHEMBL2280000 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737884-B1 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | UNIV QUEENSLAND (AU) | 2016-10-19 | — | — | EP | disclosed |
| CN-101356159-A | Substituted isoquinoline-1, 3(2H,4H) -diones, 1-thio-1, 4-dihydro-2H-isoquinoline-3-ones and 1, 4-dihydro-3 (2H) -isoquinolones and their use as kinase inhibitors | WYETH CORP (US) | 2009-01-28 | — | — | CN | disclosed |
| EP-1737884-A4 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | UNIV QUEENSLAND (AU) | 2008-10-29 | — | — | EP | disclosed |
| EP-1737884-A1 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | The University of Queensland (AU) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005090388-A1 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | THE UNIVERSITY OF QUEENSLAND (AU) | 2005-09-29 | — | — | WO | disclosed |
| CN-1351602-A | Novel Pharmaceutically Active Compounds | ASTRAZENECA AB (SE) | 2002-05-29 | — | — | CN | disclosed |