Dimethylformamide

Dimethylformamide

SCHEMBL124684

CN(C)C=O.COC(C)OC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL2184966 1.00 TSHR (0.53) TSHR
Dimethylformamide SCHEMBL1743640 0.88 TSHR (0.41) TSHR
Dimethylformamide SCHEMBL3152670 0.88 TSHR (0.41) TSHR
Dimethylformamide SCHEMBL3928720 0.86 TSHR (0.39) TSHR
Tetrahydrofuran SCHEMBL8618960 0.82 TSHR (0.36) TSHR
Dimethylformamide SCHEMBL4594404 0.81 TSHR (0.60) TSHR
SCHEMBL8493185 0.78 ALOX15 (0.30) TSHR
Acetaldehyde SCHEMBL1401397 0.78 TSHR (0.43) TSHR
SCHEMBL3207667 0.78 ALDH1A1 (0.36)
Acetaldehyde SCHEMBL225414 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6572 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295095-A1 NOVEL FUSED-HETEROCYCLYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-09-21 US claimed
US-20230286953-A1 METHODS AND INTERMEDIATES FOR PREPARING JAK INHIBITORS SUN PHARMACEUTICAL INDUSTRIES, INC. 2023-09-14 US claimed
EP-4172147-A1 METHODS AND INTERMEDIATES FOR PREPARING JAK INHIBITORS Concert Pharmaceuticals Inc. (US) 2023-05-03 EP claimed
EP-4169905-A1 NOVEL FUSED HETEROCYCLIC CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF Korea Institute of Science and Technology (KR) 2023-04-26 EP claimed
CN-115989226-A Processes and intermediates for preparing JAK inhibitors 康塞特医药品有限公司 2023-04-18 CN claimed
US-20220259146-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO LTD (KR) 2022-08-18 US claimed
EP-3527573-B9 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES INC (US) 2022-07-06 EP claimed
US-11345660-B2 Method for preparing intermediate of 4-methoxypyrrole derivative DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2022-05-31 US claimed
WO-2022006136-A1 METHODS AND INTERMEDIATES FOR PREPARING JAK INHIBITORS CONCERT PHARMACEUTICALS, INC. (US) 2022-01-06 WO claimed
WO-2021256899-A1 NOVEL FUSED HETEROCYCLIC CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF 한국과학기술연구원 2021-12-23 WO claimed
US-4625033-A 3-METHYL-4-NITROPYRIDINE-1-OXIDE CONDENSED TO ENAMINE, CATALYTIC REDUCTION CYCLIZATION SANOFI (FR) 1986-11-25 US claimed
EP-0068384-B1 17-CYCLOPROPYLMETHYL-3-HYDROXY-14-METHOXY 7 ALPHA-METHYLMORPHINAN-6-ONE MILES LABORATORIES, INC. (US) 1985-01-23 EP claimed
US-4420623-A ANTIBIOTICS THE UPJOHN COMPANY (US) 1983-12-13 US claimed
US-4379090-A Process for the preparation of 1-(phenyl and halophenyl)-3,4-dihydro-4-[(dimethylamino)methylene]5H-2-benzazepin-5-one-2-oxides HOFFMANN-LA ROCHE INC. (US) 1983-04-05 US claimed
EP-0072137-A1 Antiviral deoxyuridine compounds BEECHAM GROUP PLC (GB) 1983-02-16 EP claimed
US-4338441-A CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND WILLIAM H. RORER, INC. (US) 1982-07-06 US claimed
EP-0016277-B1 2-CARBONYL-3-HYDROXY-ALKENONITRILES, THEIR USE AS ANTI-ARTHRITIC AGENTS AND PROCESSES FOR THEIR PREPARATION AMERICAN CYANAMID COMPANY (US) 1981-12-02 EP claimed
EP-0016277-A1 2-Carbonyl-3-hydroxy-alkenonitriles, their use as anti-arthritic agents and processes for their preparation AMERICAN CYANAMID COMPANY (US) 1980-10-01 EP claimed
WO-1980000964-A1 ANTI-INFLAMMATORY AGENTS INCLUDING 2-CARBONYL-3-HYDROXY-2-ALKENONITRILES AMERICAN CYANAMID CO (US) 1980-05-15 WO claimed
US-3952007-A Processes for preparing 5-nitro-1-methyl-2-(2-dialkylaminovinyl)-imidazole and 5-nitro-1-methyl-2-imidazolyl carboxaldehyde SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed