Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.56 |
| ▸ | MMP8 | P22894 | 3/20 | 0.56 |
| ▸ | MMP12 | P39900 | 3/20 | 0.56 |
| ▸ | MMP14 | P50281 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407291 | 0.89 | ALDH1A1 (0.65) | ALDH1A1TBXA2RRAB9AEPHX2LMNA | |
| SCHEMBL4594049 | 0.86 | ALDH1A1 (0.76) | ALDH1A1TBXA2RLMNAPKMHDAC1 | |
| Bicarbonate SCHEMBL9492528 | 0.84 | ALDH1A1 (0.74) | ALDH1A1TBXA2REPHX2LMNAKDM4E | |
| Bicarbonate SCHEMBL9491178 | 0.84 | ALDH1A1 (0.74) | ALDH1A1TBXA2REPHX2LMNAKDM4E | |
| Bicarbonate SCHEMBL27679772 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TBXA2REPHX2LMNAKDM4E | |
| SCHEMBL16758295 | 0.83 | EPHX2 (0.60) | ALDH1A1EPHX2LMNAKDM4EPKM | |
| SCHEMBL6181694 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TBXA2RRAB9AEPHX2LMNA | |
| SCHEMBL1279062 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TBXA2REPHX2LMNAKDM4E | |
| SCHEMBL579136 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TBXA2REPHX2LMNAKDM4E | |
| SCHEMBL578832 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TBXA2REPHX2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873200-A1 | An improved process for making an external plasticization of aliphatic polyamides and plasticizers useful for said plasticization | Arkema France (FR) | 2008-01-02 | — | — | EP | disclosed |