SCHEMBL4594727

SCHEMBL4594727

O=C1CCC(=O)C2=C1C(=O)OC2=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 2/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55174 0.65
SCHEMBL11700035 0.65 TSHR (0.41) TSHRALOX15TDP1ALDH1A1LMNA
SCHEMBL21878867 0.63
SCHEMBL21878918 0.63
SCHEMBL11405770 0.62 TSHR (0.39) TSHRALOX15TDP1ALDH1A1LMNA
SCHEMBL3414155 0.61 ALOX15 (0.33) ALOX15TDP1
SCHEMBL13140102 0.61 TSHR (0.32) TSHR
SCHEMBL3414157 0.61 ALOX15 (0.33) ALOX15TDP1
SCHEMBL252317 0.60 TSHR (0.37) TSHRALOX15TDP1ALDH1A1LMNA
SCHEMBL10618947 0.60 CRBN (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183058-B1 ANTI-INFECTIVE MEDICAL DEVICE AND PRODUCTION METHOD OXIBIO INC (US) 2008-01-02 EP disclosed
EP-1813293-A2 ANTI-INFECTIVE MEDICAL DEVICE AND PRODUCTION METHOD Oxibio, Inc. (US) 2007-08-01 EP disclosed
US-6939569-B1 Medical device having anti-infective and contraceptive properties OXIBIO, INC. (US) 2005-09-06 US disclosed
US-6838050-B1 Methods and devices for providing anti-infective activity to a medical device OXIBIO, INC. (US) 2005-01-04 US disclosed
EP-1087800-B1 IMPLANTABLE MEDICAL DEVICE HAVING ANTI-INFECTIVE AND CONTRACEPTIVE PROPERTIES OXIBIO INC (US) 2003-08-06 EP disclosed
EP-1183058-A1 ANTI-INFECTIVE MEDICAL DEVICE AND PRODUCTION METHOD Oxibio, Inc. (US) 2002-03-06 EP disclosed
EP-1087800-A1 MEDICAL DEVICE HAVING ANTI-INFECTIVE AND CONTRACEPTIVE PROPERTIES Oxibio, Inc. (US) 2001-04-04 EP disclosed
WO-2000074743-A1 ANTI-INFECTIVE MEDICAL DEVICE AND PRODUCTION METHOD OXIBIO, INC. (US) 2000-12-14 WO disclosed
WO-1999065538-A9 MEDICAL DEVICE HAVING ANTI-INFECTIVE AND CONTRACEPTIVE PROPERTIES OXIBIO INC (US) 2000-10-12 WO disclosed
WO-1999065538-A1 MEDICAL DEVICE HAVING ANTI-INFECTIVE AND CONTRACEPTIVE PROPERTIES OXIBIO, INC. (US) 1999-12-23 WO disclosed