Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594620 | 0.96 | ALOX5AP (0.69) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4593344 | 0.94 | ALOX5AP (0.68) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4594316 | 0.94 | ALOX5AP (0.67) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4595050 | 0.94 | ALOX5AP (0.67) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL5986954 | 0.94 | ALOX5AP (0.67) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL2107903 | 0.93 | ALOX5AP (0.81) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4593233 | 0.93 | ALOX5AP (0.65) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4593700 | 0.90 | ALOX5AP (0.61) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL9048306 | 0.89 | ALOX5AP (0.84) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4594712 | 0.89 | ALOX5AP (0.62) | ALOX5APALOX5PTGS1PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871908-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2008-01-02 | — | — | EP | disclosed |
| EP-1718284-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2006-11-08 | — | — | EP | disclosed |
| WO-2006105439-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE. AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2006-10-05 | — | — | WO | disclosed |
| EP-1579010-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2005-09-28 | — | — | EP | disclosed |
| WO-2005075022-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFRACTION, STROKE, AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2005-08-18 | — | — | WO | disclosed |
| WO-2004035741-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2004-04-29 | — | — | WO | disclosed |