SCHEMBL4595129

SCHEMBL4595129

CCC(N)N1c2ccccc2Sc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
PTGS1 P23219 3/20 0.46
PTGS2 P35354 2/20 0.46
BCHE P06276 7/20 0.45
MAPT P10636 4/20 0.45
CYP2D6 P10635 4/20 0.45
ALDH1A1 P00352 3/20 0.45
ALOX15 P16050 3/20 0.45
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
ALOX12 P18054 2/20 0.45
ACHE P22303 2/20 0.45
SLC22A1 O15245 2/20 0.45
CYP1A2 P05177 2/20 0.45
CHRM2 P08172 2/20 0.45
HTR1A P08908 2/20 0.45
ADRA2A P08913 2/20 0.45
CHRM1 P11229 2/20 0.45
DRD1 P21728 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9539812 0.82 HDAC3 (0.50) BCHEMAPTCYP2D6HSD17B10ACHE
SCHEMBL12386881 0.79 PTGS1 (0.51) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL2921643 0.79 MAOA (0.54) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL13485697 0.75 CYP2D6 (0.53) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL30184394 0.74 MAOA (0.58) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL627482 0.74 MAOA (0.58) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL29022155 0.73 PTGS1 (0.45) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL502506 0.73 BCHE (0.55) BCHEMAPTCYP2D6ACHEHTR1A
SCHEMBL29830704 0.73 PTGS1 (0.45) MAOAPTGS1PTGS2BCHEMAPT
SCHEMBL6276192 0.71 BCHE (0.47) MAOAPTGS1PTGS2BCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744429-A FLOW CONTROL AGENTS EXXON CHEMICAL PATENTS INC (US) 1998-04-28 US claimed
EP-0375503-B1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1996-02-28 EP claimed
US-5055213-A Addition copolymers containing maleic anhydride monomer modifi ed by a phenothiazine derivative, napthtylamine or diphenylami ne; antideposit agents; dispersants; oxidation resistance SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-10-08 US claimed
EP-1355961-B1 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS EXXONMOBIL CHEM PATENTS INC (US) 2008-01-02 EP disclosed
US-7053153-B2 Ethylene copolymer compositions suitable for viscosity index improvers and lubricant compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-30 US disclosed
US-20040034168-A1 Ethylene copolymer compositions suitable for viscosity index improvers and lubricant compositions SCHAUDER JEAN-ROCH (BE) 2004-02-19 US disclosed
EP-1355961-A2 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2003-10-29 EP disclosed
EP-0775189-B1 LUBRICATING OILS COMPRISING LOW SATURATE BASESTOCK INFINEUM USA LP (US) 2003-01-22 EP disclosed
WO-2002046251-A2 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-13 WO disclosed
US-5932525-A INTERNAL COMBUSTION ENGINE MULTIGRADE LUBRICATING OIL CONTAINING A MIXTURE OF GREATER THAN 20% AROMATICS, LESS THAN 70% SATURATED HYDROCARBONS, ASHLESS DETERGENT, AND MULTIFUNCTIONAL VISCOSITY MODIFIER; ANTI-VARNISH AGENTS EXXON CHEMICAL PATENTS, INC. (US) 1999-08-03 US disclosed
EP-0673407-B1 MIXED ETHYLENE ALPHA OLEFIN COPOLYMER MULTIFUNCTIONAL VISCOSITY MODIFIERS USEFUL IN LUBE OIL COMPOSITIONS EXXON CHEMICAL PATENTS INC (US) 1998-10-07 EP disclosed
EP-0375503-B1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1996-02-28 EP disclosed
EP-0673407-A1 MIXED ETHYLENE ALPHA OLEFIN COPOLYMER MULTIFUNCTIONAL VISCOSITY MODIFIERS USEFUL IN LUBE OIL COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1995-09-27 EP disclosed
US-5427702-A Mixture of copolymers with different amounts of ethylene functionalized with acid groups and nucleophilic amine EXXON CHEMICAL PATENTS INC. (US) 1995-06-27 US disclosed
WO-1994013763-A1 MIXED ETHYLENE ALPHA OLEFIN COPOLYMER MULTIFUNCTIONAL VISCOSITY MODIFIERS USEFUL IN LUBE OIL COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1994-06-23 WO disclosed
US-5269954-A Nitrogenous additives with an antioxidant action and lubricating compositions containing the said additives ELF FRANCE (FR) 1993-12-14 US disclosed
EP-0377358-B1 NITROGEN-BEARING ADDITIVES HAVING ANTIOXIDANT PROPERTIES, AND LUBRICANT COMPOSITIONS COMPRISING SAME ELF ANTAR FRANCE (FR) 1993-03-24 EP disclosed
US-5055213-A Addition copolymers containing maleic anhydride monomer modifi ed by a phenothiazine derivative, napthtylamine or diphenylami ne; antideposit agents; dispersants; oxidation resistance SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-10-08 US disclosed
EP-0377358-A2 Nitrogen-bearing additives having antioxidant properties, and lubricant compositions comprising same ELF ANTAR FRANCE (FR) 1990-07-11 EP disclosed
EP-0375503-A1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1990-06-27 EP disclosed