Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 8/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619274 | 0.94 | AR (0.46) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4595452 | 0.88 | AR (0.48) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4595549 | 0.87 | AR (0.47) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4595035 | 0.85 | AR (0.46) | ARPGR | |
| SCHEMBL4904337 | 0.76 | AR (0.54) | ARPGRDPP4DPP7S1PR1 | |
| SCHEMBL3039891 | 0.75 | AR (0.52) | ARPGRRXRARXRBRXRG | |
| Trifluoroacetic Acid SCHEMBL3419464 | 0.74 | AR (0.48) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4595496 | 0.74 | AR (0.66) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL3060320 | 0.73 | AR (0.53) | ARPGR | |
| SCHEMBL3048408 | 0.73 | AR (0.54) | ARPGRRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871379-A2 | CYANOARYLAMINES | Smithkline Beecham Corporation (US) | 2008-01-02 | — | — | EP | claimed |
| WO-2006113552-A2 | CYANOARYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-26 | — | — | WO | claimed |
| EP-1871379-A2 | CYANOARYLAMINES | Smithkline Beecham Corporation (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006113552-A2 | CYANOARYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |