SCHEMBL4595272

SCHEMBL4595272

CC(=O)OCCNS(=O)(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.65
MAPK1 P28482 1/20 0.58
KDM4E B2RXH2 2/20 0.54
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
PKM P14618 1/20 0.54
TSHR P16473 1/20 0.54
TBXA2R P21731 1/20 0.53
NEK1 Q96PY6 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
HTT P42858 1/20 0.51
USP2 O75604 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
MAPT P10636 2/20 0.49
NPC1 O15118 1/20 0.49
HPGD P15428 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680369 0.86 ALDH1A1 (0.69) ALDH1A1KDM4ELMNASMN1; SMN2NEK1
SCHEMBL3249912 0.85 ALDH1A1 (0.62) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL27479167 0.84 ALDH1A1 (0.61) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL27583651 0.84 ALDH1A1 (0.57) ALDH1A1KDM4ELMNASMN1; SMN2PKM
SCHEMBL28838198 0.84 ALDH1A1 (0.65) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL18406853 0.83 ALDH1A1 (0.63) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL2011303 0.82 HDAC1 (0.60) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL18405634 0.81 ALDH1A1 (0.56) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL9568633 0.80 ALDH1A1 (0.59) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2
SCHEMBL18405671 0.80 ALDH1A1 (0.55) ALDH1A1MAPK1KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929603-B1 PLASTICISED POLYMER COMPOSITIONS UCB SA (BE) 2003-12-03 EP claimed
US-6624218-B2 A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding UCB, S.A. (BE) 2003-09-23 US claimed
US-20020165301-A1 Plasticized polymer compositions UCB, S.A. 2002-11-07 US claimed
EP-0929603-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1999-07-21 EP claimed
WO-1998014513-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1998-04-09 WO claimed
EP-4444798-A1 ACID RESISTANT POLYOXYMETHYLENE COMPOSITION AND ARTICLES MADE THEREWITH Celanese International Corporation (US) 2024-10-16 EP disclosed
US-12076913-B2 Feed material for three-dimensional printing containing a polyoxymethylene polymer TICONA LLC (US) 2024-09-03 US disclosed
US-11939467-B2 Polyoxymethylene polymer composition that is chemical resistant TICONA LLC (US) 2024-03-26 US disclosed
EP-4294896-A1 POLYOXYMETHYLENE POLYMER COMPOSITION THAT IS MEDIA RESISTANT Celanese International Corporation (US) 2023-12-27 EP disclosed
CN-117178049-A Medium-resistant polyoxymethylene polymer compositions 国际人造丝公司 2023-12-05 CN disclosed
US-20230183476-A1 Acid Resistant Polyoxymethylene Composition and Articles Made Therewith CELANESE INTERNATIONAL CORPORATION 2023-06-15 US disclosed
WO-2023107679-A1 ACID RESISTANT POLYOXYMETHYLENE COMPOSITION AND ARTICLES MADE THEREWITH CELANESE INTERNATIONAL CORPORATION (US) 2023-06-15 WO disclosed
WO-2012049287-A1 PLASTICIZED POLYOXYMETHYLENE TICONA GMBH (DE) 2012-04-19 WO disclosed
EP-1873200-A1 An improved process for making an external plasticization of aliphatic polyamides and plasticizers useful for said plasticization Arkema France (FR) 2008-01-02 EP disclosed
EP-0929603-B1 PLASTICISED POLYMER COMPOSITIONS UCB SA (BE) 2003-12-03 EP disclosed
US-6624218-B2 A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding UCB, S.A. (BE) 2003-09-23 US disclosed
US-20020165301-A1 Plasticized polymer compositions UCB, S.A. 2002-11-07 US disclosed
US-6384115-B1 Plasticized polymer compositions UCB, S.A. (BE) 2002-05-07 US disclosed
EP-0929603-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1999-07-21 EP disclosed
WO-1998014513-A1 PLASTICISED POLYMER COMPOSITIONS UCB, S.A. (BE) 1998-04-09 WO disclosed