Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.63 |
| ▸ | RET | P07949 | 7/20 | 0.46 |
| ▸ | PIM1 | P11309 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595307 | 0.83 | FYN (0.63) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL4333737 | 0.80 | RET (0.65) | FYNRETMEN1KMT2AKDR | |
| SCHEMBL4333521 | 0.79 | FYN (0.81) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL4331853 | 0.77 | FYN (0.66) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL30521762 | 0.77 | FYN (1.00) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL4334408 | 0.77 | FYN (1.00) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL4333742 | 0.77 | FYN (0.45) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL20081017 | 0.77 | FYN (0.64) | FYNPIM1MEN1KMT2ATGFBR2 | |
| SCHEMBL4331236 | 0.76 | PIM1 (0.64) | FYNRETPIM1MEN1KMT2A | |
| SCHEMBL4595305 | 0.74 | FYN (0.43) | FYNRETMEN1KMT2ATGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873157-A1 | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-02 | — | — | EP | disclosed |