SCHEMBL4595586

SCHEMBL4595586

C=CC(=O)Oc1cccc(C)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.51
MAPT P10636 3/20 0.47
THRB P10828 3/20 0.47
THRA P10827 1/20 0.47
TYMS P04818 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALDH1A1 P00352 2/20 0.40
ACHE P22303 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTR1B P28222 1/20 0.38
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1058506 0.85 THRB (0.53) MAPTTHRBTHRATYMSMEN1
SCHEMBL30577103 0.85 THRB (0.53) MAPTTHRBTHRATYMSMEN1
SCHEMBL11040964 0.85 POLB (0.54) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL11041012 0.85 POLB (0.54) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL5147452 0.84 THRB (0.46) POLBMAPTTHRBTHRATYMS
SCHEMBL9309688 0.84 POLB (0.53) POLBMAPTMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL19749006 0.84 THRB (0.51) MAPTTHRBTHRATYMSMEN1
SCHEMBL14776596 0.84 THRB (0.41) POLBMAPTTHRBTHRATYMS
SCHEMBL26041847 0.83 THRB (0.44) POLBMAPTTHRBTHRATYMS
SCHEMBL13588231 0.83 TYMS (0.49) POLBMAPTTHRBTHRATYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59082343-A None JP disclosed
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 US disclosed
US-20240309155-A1 Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms INFINEUM INTERNATIONAL LIMITED (GB) 2024-09-19 US disclosed
CN-117623924-A Preparation method and application of trisubstituted olefin 苏州新启材料科技有限公司 2024-03-01 CN disclosed
EP-3587491-B1 RESIN COMPOSITION CONTAINING POLYMER PARTICLES KURARAY CO (JP) 2024-01-31 EP disclosed
EP-4267708-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS Infineum International Limited (GB) 2023-11-01 EP disclosed
CN-116981758-A Thermally responsive brush polymers having a copolymer backbone and copolymer arms 英菲诺姆国际有限公司 2023-10-31 CN disclosed
CN-115023413-A Rearrangement of dimethylphenyl acrylate using zeolite 帝斯曼知识产权资产管理有限公司 2022-09-06 CN disclosed
CN-115023413-A Rearrangement of dimethylphenyl acrylate using zeolite 帝斯曼知识产权资产管理有限公司 2022-09-06 CN disclosed
EP-0832136-A1 POLYMER SUPPORTED CATALYST FOR OLEFIN POLYMERIZATION QUANTUM CHEMICAL CORPORATION (US) 1998-04-01 EP disclosed
EP-0825897-A1 POLYMER-SUPPORTED CATALYST FOR OLEFIN POLYMERIZATION QUANTUM CHEMICAL CORPORATION (US) 1998-03-04 EP disclosed
US-5587439-A COORDINATION CATALYSTS QUANTUM CHEMICAL CORPORATION (US) 1996-12-24 US disclosed
US-5587486-A CONDENSATION; CARBONYLATION; HYDROLYSIS; INTERMEDIATES IN THE PRODUCTION OF MEDICINAL AND AGRICULTURAL AGENTS KURARAY CO., LTD. (JP) 1996-12-24 US disclosed
WO-1996035726-A1 POLYMER SUPPORTED CATALYST FOR OLEFIN POLYMERIZATION QUANTUM CHEMICAL CORPORATION (US) 1996-11-14 WO disclosed
WO-1996030122-A1 POLYMER-SUPPORTED CATALYST FOR OLEFIN POLYMERIZATION QUANTUM CHEMICAL CORPORATION (US) 1996-10-03 WO disclosed
EP-0690054-A1 1-Amino-2-cyclohexene derivatives and production process therefor KURARAY CO., LTD. (JP) 1996-01-03 EP disclosed
US-4581312-A COPOLYMER OF A STYRENE AND TERTIARY AMINO VINYL MONOMER CANON KABUSHIKI KAISHA (JP) 1986-04-08 US disclosed
JP-S5982343-A PREPARATION OF XYLYL ACRYLATE OR XYLYL METHACRYLATE NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1984-05-12 JP disclosed
US-4059618-A CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed