SCHEMBL4595838

SCHEMBL4595838

CC(C)c1cccc(C(=O)CC(=O)c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CYP3A4 P08684 3/20 0.59
HPGD P15428 3/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
KDM4E B2RXH2 2/20 0.59
MAPK1 P28482 2/20 0.59
ALOX15 P16050 1/20 0.59
CES1 P23141 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
KAT6A Q92794 3/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 1/20 0.53
PTGS1 P23219 3/20 0.50
PTGS2 P35354 3/20 0.50
CXCR1 P25024 2/20 0.50
CXCR2 P25025 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HIF1A Q16665 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18300779 0.87 ERCC5 (0.59) MAPTSMN1; SMN2CYP3A4HPGDKDM4E
SCHEMBL5306428 0.85 ALDH1A1 (0.52) MAPTSMN1; SMN2CYP3A4HPGDMEN1
Dibenzoylmethane SCHEMBL5680105 0.84 KMT2A (0.65) MAPTSMN1; SMN2CYP3A4HPGDMEN1
SCHEMBL38900 0.84 KMT2A (0.65) MAPTSMN1; SMN2CYP3A4HPGDMEN1
SCHEMBL6580274 0.82 TP53BP1 (0.48) MAPTSMN1; SMN2CYP3A4HPGDMEN1
SCHEMBL4227994 0.82 TP53BP1 (0.48) MAPTSMN1; SMN2CYP3A4HPGDKDM4E
SCHEMBL1505219 0.82 MRGPRX4 (0.55) MAPTSMN1; SMN2CYP3A4HPGDMEN1
SCHEMBL4834885 0.81 MEN1 (0.81) MAPTSMN1; SMN2CYP3A4HPGDMEN1
SCHEMBL18301055 0.81 TP53BP1 (0.45) MAPTSMN1; SMN2CYP3A4HPGDKMT2A
SCHEMBL18552569 0.81 TP53BP1 (0.47) MAPTSMN1; SMN2CYP3A4HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100452-B2 COSMETIC OR DERMATOLOGICAL WATER/OIL EMULSIONS CONTAINING NONIONIC SURFACTANTS AND CHARACTERIZED BY A SILICONE EMULSIFYING AGENT CONTENT BEIERSDORF AG (DE) 2006-12-13 EP claimed
EP-0904770-B1 Use of X-Ray amorphous oxides for increasing the light protection factor and/or the UV-A protection of cosmetic and/or dermatological light protection agents BEIERSDORF AG (DE) 2004-06-30 EP claimed
EP-0998910-B1 Cosmetic and dermatologic aqueous dispersions containing triglyceridic waxes BEIERSDORF AG (DE) 2004-06-16 EP claimed
EP-0935959-B1 Use of beeswax to increase the UVA protection factor of cosmetic or dermatologic sunscreens BEIERSDORF AG (DE) 2004-03-24 EP claimed
EP-1100452-B1 COSMETIC OR DERMATOLOGICAL WATER/OIL EMULSIONS CONTAINING NONIONIC SURFACTANTS AND CHARACTERIZED BY A SILICONE EMULSIFYING AGENT CONTENT BEIERSDORF AG (DE) 2003-10-15 EP claimed
EP-1213010-A2 Use of water-soluble and film-forming polymers for increasing the light protection factor and/or the protection performance to UV-A in cosmetic or dermatological formulations Beiersdorf AG (DE) 2002-06-12 EP claimed
EP-1055410-A2 Cosmetic or dermatological sunscreen formulations containing boron nitride and ethylhexyl-2-cyano-3,3-diphenylacrylat and use of boron nitride for increasing the light protection factor and /or the UV-A protection of cosmetic or dermatologic light protection agents Beiersdorf Aktiengesellschaft (DE) 2000-11-29 EP claimed
EP-1000611-A1 Use of triglyceridic waxes to enhance the sun protecting factor of a sunscreen Beiersdorf Aktiengesellschaft (DE) 2000-05-17 EP claimed
EP-0998910-A1 Cosmetic and dermatologic aqueous dispersions containing triglyceridic waxes Beiersdorf Aktiengesellschaft (DE) 2000-05-10 EP claimed
EP-0976391-A1 Cosmetic and dermatological W/O emulsions, containing ionic and/or amphoteric detergents and the presence of an amount of silicone-emulgators Beiersdorf Aktiengesellschaft (DE) 2000-02-02 EP claimed
EP-0963753-A2 Utilisation of C20-40 dialkyldimerate for increasing the light protection factor and/or the UV-A protection of cosmetic or dermatologic light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0935959-A2 Use of beeswax to increase the protection factor of cosmetic or dermatologic sunscreens Beiersdorf Aktiengesellschaft (DE) 1999-08-18 EP claimed
EP-0922447-A2 Utilisation of C18-38 alkylhydroxystearoylsterates for increasing the light protection factor and/or the UV-A protection of cosmetic or dermatologic light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-06-16 EP claimed
EP-0904770-A1 Utilisation of X-ray-amorphous oxids for increasing the light protectionfactor and/or the UV-protection of cosmetic or dermatologie light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-03-31 EP claimed
EP-0875240-A2 Combinations or complexes of derivatives of dibenzoymethane and/or derivatives of cinnamic acid with cyclodextrins and use of the combinations in cosmetic sun protecting compositions Beiersdorf Aktiengesellschaft (DE) 1998-11-04 EP claimed
EP-0864313-A2 Use of benzophenones and their derivatives to prevent UV-induced decomposition of dibenzoylmethane and its derivatives Beiersdorf Aktiengesellschaft (DE) 1998-09-16 EP claimed
EP-1482905-B1 A PROCESS FOR PREPARING A COSMETIC FORMULATION AND A COMPOSITION THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2017-06-21 EP disclosed
EP-1062943-B1 Cosmetic or dermatologic sunscreen compositions containing boron nitride and UV filters having triazine groups BEIERSDORF AG (DE) 2008-01-09 EP disclosed
EP-0875240-A2 Combinations or complexes of derivatives of dibenzoymethane and/or derivatives of cinnamic acid with cyclodextrins and use of the combinations in cosmetic sun protecting compositions Beiersdorf Aktiengesellschaft (DE) 1998-11-04 EP disclosed
EP-0343444-A2 Cosmetic composition containing retinyl palmitate BAYER AG (DE) 1989-11-29 EP disclosed