SCHEMBL4595897

SCHEMBL4595897

CCN1c2ccccc2C=CC1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 7/20 0.37
ALDH1A1 P00352 2/20 0.37
P2RX4 Q99571 4/20 0.37
P2RX1 P51575 3/20 0.37
P2RX3 P56373 3/20 0.37
NPSR1 Q6W5P4 3/20 0.37
P2RX7 Q99572 2/20 0.37
PTBP1 P26599 1/20 0.37
MAPK1 P28482 4/20 0.36
TSHR P16473 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31536053 0.81 MEN1 (0.48) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL11792980 0.80 SMN1; SMN2 (0.46) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL3625895 0.80 SMN1; SMN2 (0.39) KMT2AMEN1SMN1; SMN2LMNAMAPT
Bromide SCHEMBL8906346 0.78 MEN1 (0.42) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL19261265 0.76 SMN1; SMN2 (0.37) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL7528724 0.76 SMN1; SMN2 (0.59) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL10824458 0.75 MEN1 (0.46) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL29896267 0.75 MEN1 (0.46) KMT2AMEN1SMN1; SMN2LMNAMAPT
SCHEMBL28742796 0.75 MEN1 (0.43) KMT2AMEN1LMNAP2RX4MAPK1
SCHEMBL20651294 0.75 MEN1 (0.51) KMT2AMEN1SMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756835-B Fluorescent probe for near-infrared detection of peroxynitroso, and preparation method and application thereof 烟台大学 2024-04-30 CN claimed
CN-117756835-A Fluorescent probe for near-infrared detection of peroxynitroso, and preparation method and application thereof 烟台大学 2024-03-26 CN claimed
CN-114605397-A Preparation and application of viscosity near-infrared fluorescent probe 湘潭大学 2022-06-10 CN claimed
CN-113429389-B Preparation and application of solid-state fluorescent probe for detecting carbon monoxide 湘潭大学 2022-05-10 CN claimed
CN-113429389-A Preparation and application of solid-state fluorescent probe for detecting carbon monoxide 湘潭大学 2021-09-24 CN claimed
CN-111825665-A Ratio type near-infrared fluorescent probe for detecting sulfur dioxide derivative and preparation method thereof 江苏大学 2020-10-27 CN claimed
EP-1502580-B1 Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles OREAL (FR) 2008-01-23 EP claimed
EP-1500387-B1 Use of ninhydrin derivatives for dyeing OREAL (FR) 2008-01-09 EP claimed
EP-1200049-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2007-02-21 EP claimed
EP-1311231-B1 AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE HENKEL KGAA (DE) 2006-11-22 EP claimed
EP-1535601-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-06-01 EP claimed
EP-1535600-A1 Use of derivatives of ninhydrin carrying an unsaturated system in colouring L'OREAL (FR) 2005-06-01 EP claimed
EP-1530963-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-05-18 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
EP-1502580-A1 Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles L'OREAL (FR) 2005-02-02 EP claimed
EP-1500387-A1 Use of ninhydrin derivatives for dyeing L'OREAL (FR) 2005-01-26 EP claimed
EP-1139990-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2004-05-06 EP claimed
EP-1139988-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2002-09-25 EP claimed
EP-1198457-A1 QUATERNIZED AZAFLUORENONES AND THEIR USE IN AGENTS FOR DYING FIBERS CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2002-04-24 EP claimed
WO-2001010840-A1 QUATERNIZED AZAFLUORENONES AND THEIR USE IN AGENTS FOR DYING FIBERS CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-02-15 WO claimed