Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 11/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50921 | 0.87 | RORC (0.51) | RORCALOX15CYP2D6TP53CYP2C9 | |
| SCHEMBL9117896 | 0.86 | RORC (0.59) | RORCALOX15CYP2D6TP53CYP2C9 | |
| SCHEMBL12435286 | 0.81 | RORC (0.57) | RORCALOX15NPC1LMNAMAPK1 | |
| SCHEMBL5523833 | 0.81 | RORC (0.53) | RORCALOX15CYP2D6NPC1LMNA | |
| SCHEMBL51093 | 0.81 | RORC (0.57) | RORCALOX15CYP2D6NPC1LMNA | |
| SCHEMBL4595074 | 0.81 | RORC (0.58) | RORCALOX15CYP2D6TP53CYP2C9 | |
| SCHEMBL11876501 | 0.80 | RORC (0.75) | RORCALOX15NPC1LMNAMAPK1 | |
| SCHEMBL9120887 | 0.80 | RORC (0.56) | RORCALOX15CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12424214 | 0.79 | RORC (0.54) | RORCALOX15CYP2D6NPC1LMNA | |
| SCHEMBL51083 | 0.78 | RORC (0.46) | RORCCYP2D6CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437231-B1 | DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS | API CORP (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-20040241598-A1 | Developer for thermal recording material and thermal recording materials | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1437231-A1 | DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS | API Corporation (JP) | 2004-07-14 | — | — | EP | disclosed |