Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622476 | 1.00 | TSHR (0.57) | TSHRTDP1ALDH1A1MEN1GMNN | |
| Propane SCHEMBL7027940 | 0.85 | TSHR (0.39) | TSHRTDP1ALDH1A1MEN1GMNN | |
| Alcohol SCHEMBL4771437 | 0.85 | TSHR (0.50) | TSHRTDP1ALDH1A1MEN1GMNN | |
| SCHEMBL229715 | 0.84 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1GMNNGABBR2 | |
| SCHEMBL19621 | 0.84 | — | — | |
| SCHEMBL27915924 | 0.83 | TSHR (0.35) | TSHRTDP1ALDH1A1 | |
| Butane SCHEMBL3273417 | 0.81 | ALDH1A1 (0.36) | TSHRTDP1ALDH1A1MEN1GMNN | |
| SCHEMBL10444 | 0.81 | — | — | |
| SCHEMBL7650639 | 0.81 | ALDH1A1 (0.33) | TSHRALDH1A1MEN1GMNNGABBR2 | |
| SCHEMBL2277021 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137727-B1 | AQUEOUS COATING COMPOSITIONS | DU PONT (US) | 2008-01-09 | — | — | EP | disclosed |
| US-6204319-B1 | AB BLOCK COPOLYMER PIGMENT DISPERSANT RESIN OF AN A BLOCK OF A HYDROPHOBIC POLYMER HAVING AMINE GROUPS; AND A B BLOCK OF A HYDROPHILIC POLYMER HAVING HYDROXYL GROUPS AND CARBOXYL GROUPS | E.I. DU PONT DE NEMOURS AND COMPANY | 2001-03-20 | — | — | US | disclosed |