SCHEMBL4596064

SCHEMBL4596064

O=C=CCCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 5/20 0.44
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KEAP1 Q14145 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146891 0.87 HDAC3 (0.45) TDP1SMN1; SMN2HTR2AMAOAMAOB
SCHEMBL11250439 0.82 MAOB (0.42) GPR52ALDH1A1HPGDALOX15ALOX12
SCHEMBL10454344 0.79 FFAR1 (0.40) GPR52SMN1; SMN2HDAC3MAPK1ADRA1A
SCHEMBL14297904 0.78 CYP1A2 (0.45) GPR52ALDH1A1ALOX15TDP1SMN1; SMN2
SCHEMBL21504037 0.78 TAAR1 (0.45) HTR2ATAAR1LOXL2MAOAMAOB
SCHEMBL5523553 0.77 MIF (0.47) GPR52ALDH1A1HPGDALOX15ALOX12
SCHEMBL3035505 0.77 MAOB (0.42) GPR52ALDH1A1HPGDALOX15ALOX12
SCHEMBL21504040 0.77 TAAR1 (0.52) ALDH1A1HPGDSMN1; SMN2TAAR1
SCHEMBL57808 0.76 MAOB (0.52) LOXL2CA1CA2MAOB
SCHEMBL43326 0.75 MAOA (0.50) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666548-B1 Phase change inks containing trans-1,2-cyclohexane bis(urea-urethane) compounds XEROX CORP (US) 2008-01-09 EP disclosed
CN-1096796-A The preparation method of urethane foam EASTMAN KODAK CO (US) 1994-12-28 CN disclosed
US-3997500-A ADDITION POLYMER THE DOW CHEMICAL COMPANY (US) 1976-12-14 US disclosed
US-3955027-A FLUOROCARBON POLYMERS, EXTENDERS THE DOW CHEMICAL COMPANY (US) 1976-05-04 US disclosed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US disclosed