SCHEMBL4596111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11387013	0.85	AKR1C3 (0.50)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597658	0.83	AKR1C3 (0.74)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	Hydrochloric Acid SCHEMBL11157153	0.83	AKR1C3 (0.49)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597117	0.82	PSEN1 (0.72)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597477	0.81	AKR1C3 (0.56)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597558	0.81	AKR1C3 (0.65)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL6477785	0.80	PSEN1 (0.54)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597386	0.79	PSEN1 (0.54)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597484	0.77	PSEN1 (0.52)	AKR1C3AKR1C2PSEN1PSEN2APH1B
	SCHEMBL4597051	0.77	AKR1C3 (0.51)	AKR1C3AKR1C2PSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.