⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397289 | 0.60 | — | — | |
| SCHEMBL16486499 | 0.57 | — | — | |
| SCHEMBL1515843 | 0.56 | — | — | |
| SCHEMBL2479756 | 0.56 | — | — | |
| SCHEMBL580176 | 0.53 | — | — | |
| SCHEMBL1756035 | 0.53 | — | — | |
| SCHEMBL11106991 | 0.50 | — | — | |
| SCHEMBL4296685 | 0.46 | — | — | |
| SCHEMBL320324 | 0.45 | — | — | |
| Methenamine SCHEMBL3096283 | 0.42 | MAPT (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893470-B1 | Keratinous fibre oxidation dyeing composition containing a laccase and dyeing method using same | L'OREAL S.A. (FR) | 2005-05-17 | — | — | US | claimed |
| JP-2003517466-A | — | — | 2003-05-27 | — | — | JP | claimed |
| EP-1218380-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES WHICH ARE SUBSTITUTED ON THE SIXTH RING | Grünenthal GmbH (DE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001027110-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES WHICH ARE SUBSTITUTED ON THE SIXTH RING | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| CN-110156813-B | Heterocyclic compounds as TRK inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-113563341-B | Substituted pyrazolo [1,5-a ] pyrimidine compounds as Trk inhibitors | 山东轩硕医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113563341-A | Substituted pyrazolo [1,5-a ] pyrimidine compounds as Trk inhibitors | 南京雷正医药科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| WO-2021018445-A1 | OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2021-02-04 | — | — | WO | disclosed |
| WO-2013069166-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013069168-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013069165-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013069167-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| EP-1651181-A1 | DYEING COMPOSITION COMPRISING AT LEAST ONE DYE PRECURSOR AND ONE AMPHIPHILIC BLOCK COPOLYMER | L'OREAL (FR) | 2006-05-03 | — | — | EP | disclosed |
| WO-2006042626-A1 | DEPILATION AGENT OR COLOR-CHANGING OR SHAPE-CHANGING FIBER TREATMENT AGENTS WITH ACTIVE SUBSTANCES FOR STIMULATING THE RELEASE OF $G(B)-ENDORPHIN IN KERATINOCYTES | HANS SCHWARZKOPF & HENKEL GMBH & CO. KG (DE) | 2006-04-27 | — | — | WO | disclosed |
| WO-2005013929-A1 | COMPOSITION FOR DYEING HUMAN KERATIN FIBRES, COMPRISING A 1H-PYRAZOLYL-ETHENYL-INDOLIUM DERIVATIVE | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |
| WO-2004111062-A1 | PARA-PHENYLENEDIAMINE DERIVATIVES COMPRISING A DIAZACYCLOHEPTANE RING SUBSTITUTED WITH A SILYL RADICAL, FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004103327-A1 | DYEING COMPOSITION COMPRISING AT LEAST ONE DYE PRECURSOR AND ONE AMPHIPHILIC BLOCK COPOLYMER | L'OREAL (FR) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004043417-A2 | COMPOSITION FOR DYEING KERATIN FIBRES CONTAINING A DYE PRECURSOR AND AN ENZYME WITH NITROREDUCTASE ACTIVITY | L'OREAL (FR) | 2004-05-27 | — | — | WO | disclosed |
| EP-1218380-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES WHICH ARE SUBSTITUTED ON THE SIXTH RING | Grünenthal GmbH (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001027110-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES WHICH ARE SUBSTITUTED ON THE SIXTH RING | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | disclosed |