Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561722 | 0.89 | MEN1 (0.40) | MEN1KMT2ACYP11B1CYP11B2CA12 | |
| SCHEMBL16791932 | 0.88 | MEN1 (0.39) | MEN1KMT2ACYP11B1CYP11B2CA12 | |
| SCHEMBL29829964 | 0.85 | CYP11B1 (0.49) | MEN1KMT2ACYP11B1CYP11B2CA12 | |
| SCHEMBL5114144 | 0.85 | CYP11B1 (0.49) | MEN1KMT2ACYP11B1CYP11B2CA12 | |
| SCHEMBL10175176 | 0.83 | CYP2C19 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3644242 | 0.83 | MEN1 (0.36) | MEN1KMT2ACYP11B1CYP11B2POLB | |
| SCHEMBL20395635 | 0.81 | CHRNB4 (0.39) | MEN1KMT2ACYP11B1CYP11B2CA12 | |
| SCHEMBL17014448 | 0.80 | CCNC (0.47) | MEN1KMT2APOLBGPR119GAA | |
| SCHEMBL24435133 | 0.79 | CA12 (0.37) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL26272362 | 0.79 | ALOX5 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |