Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584828 | 1.00 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL3583025 | 1.00 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL18411348 | 0.84 | SIGMAR1 (0.53) | SIGMAR1MEN1KMT2A | |
| SCHEMBL14460139 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL13936121 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL14401346 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MLNR | |
| SCHEMBL5058871 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MLNR | |
| SCHEMBL3165725 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MLNR | |
| SCHEMBL4678046 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MLNR | |
| SCHEMBL5060895 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874315-A2 | COMPOSITIONS OF NOVEL OPIOID COMPOUNDS AND METHOD OF USE THEREOF | Mount Cook Biosciences, Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007027987-A2 | METHOD OF TREATING PARKINSON'S DISEASE WITH DIARYLMETHYLPIPERAZINE COMPOUNDS EXHIBITING DELTA RECEPTOR AGONIST ACTIVITY | MOUNT COOK BIOSCIENCES, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2006113468-A2 | COMPOSITIONS OF NOVEL OPIOID COMPOUNDS AND METHOD OF USE THEREOF | MOUNT COOK BIOSCIENCES, INC. (US) | 2006-10-26 | — | — | WO | disclosed |