Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CDK4 | P11802 | 4/20 | 0.50 |
| ▸ | CCND1 | P24385 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18405592 | 0.80 | CDK4 (0.57) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL418336 | 0.79 | CDK4 (0.61) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL13157277 | 0.76 | CDK4 (0.57) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL20427954 | 0.76 | AR (0.62) | KMT2AMAPK1LMNAKDM4EMEN1 | |
| SCHEMBL18965027 | 0.76 | AR (0.62) | KMT2AMAPK1LMNAKDM4EMEN1 | |
| SCHEMBL27547508 | 0.75 | CDK4 (0.65) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL29420405 | 0.74 | KMT2A (1.00) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL1598786 | 0.74 | KMT2A (1.00) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL24109782 | 0.73 | HTR2A (0.56) | KMT2ACDK4CCND1MAPK1LMNA | |
| SCHEMBL10165541 | 0.73 | LMNA (0.65) | KMT2ACDK4CCND1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874723-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | Dominion Pharmakine S.L. (ES) | 2008-01-09 | — | — | EP | claimed |
| WO-2006108864-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2006-10-19 | — | — | WO | claimed |
| EP-1874723-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | Dominion Pharmakine S.L. (ES) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108864-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2006-10-19 | — | — | WO | disclosed |