Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576591 | 1.00 | CCR5 (0.43) | CCR5CHRM2CHRM3NSD3 | |
| SCHEMBL5576594 | 1.00 | CCR5 (0.43) | CCR5CHRM2CHRM3NSD3 | |
| SCHEMBL5576598 | 1.00 | CCR5 (0.43) | CCR5CHRM2CHRM3NSD3 | |
| SCHEMBL5572538 | 0.88 | CCR5 (0.41) | CCR5 | |
| SCHEMBL3754244 | 0.83 | CCR5 (0.53) | CCR5 | |
| SCHEMBL3754248 | 0.83 | CCR5 (0.53) | CCR5 | |
| SCHEMBL4415837 | 0.83 | CCR5 (0.60) | CCR5 | |
| SCHEMBL4552225 | 0.83 | CCR5 (0.60) | CCR5 | |
| SCHEMBL4610281 | 0.80 | CCR5 (0.52) | CCR5CHRM2CHRM3 | |
| SCHEMBL5575895 | 0.80 | CCR5 (0.52) | CCR5CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |