Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747216 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1NSD3CCR5KMT2A | |
| Dimethylformamide SCHEMBL27747192 | 0.91 | NSD3 (0.36) | SLC18A3SIGMAR1NSD3CCR5KMT2A | |
| SCHEMBL5575622 | 0.90 | NSD3 (0.40) | SLC18A3SIGMAR1NSD3CCR5KMT2A | |
| SCHEMBL4596166 | 0.90 | NSD3 (0.40) | SLC18A3SIGMAR1NSD3CCR5KMT2A | |
| SCHEMBL4598194 | 0.86 | CCR5 (0.41) | SLC18A3SIGMAR1NSD3CCR5 | |
| SCHEMBL4597856 | 0.86 | CCR5 (0.45) | SLC18A3SIGMAR1NSD3CCR5 | |
| SCHEMBL4597464 | 0.86 | CCR5 (0.39) | NSD3CCR5 | |
| SCHEMBL4597932 | 0.86 | MEN1 (0.47) | NSD3CCR5KMT2AMEN1SLC6A2 | |
| SCHEMBL5575040 | 0.86 | MEN1 (0.47) | NSD3CCR5KMT2AMEN1SLC6A2 | |
| SCHEMBL4596330 | 0.84 | MAPT (0.44) | NSD3CCR5KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309690-A | Chemokine receptor binding compounds | ANORMED INC (CA) | 2008-11-19 | — | — | CN | disclosed |
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |