Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604304 | 1.00 | SLC18A3 (0.44) | SLC18A3SIGMAR1HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL3253412 | 0.89 | CALCRL (0.43) | SLC18A3SIGMAR1HTR2CHTR2BHTR2A | |
| SCHEMBL3248250 | 0.85 | CALCRL (0.38) | HTR2CHTR2BHTR2ANSD3HPGD | |
| SCHEMBL3247820 | 0.85 | MEN1 (0.37) | HTR2CHTR2BHTR2AKMT2ATP53 | |
| SCHEMBL4608509 | 0.84 | HTR2C (0.54) | HTR2CHTR2BHTR2ANSD3HTR6 | |
| SCHEMBL4597774 | 0.84 | HTR2C (0.54) | HTR2CHTR2BHTR2ANSD3HTR6 | |
| SCHEMBL20986870 | 0.82 | PARP1 (0.41) | HTR2CHTR2BHTR6PARP1 | |
| SCHEMBL20986734 | 0.82 | PARP1 (0.41) | HTR2CHTR2BHTR6PARP1 | |
| SCHEMBL20986544 | 0.82 | PARP1 (0.41) | HTR2CHTR2BHTR6PARP1 | |
| SCHEMBL20986540 | 0.82 | PARP1 (0.41) | HTR2CHTR2BHTR6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |