⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914021 | 0.71 | TRIM24 (0.30) | — | |
| SCHEMBL1551749 | 0.69 | — | — | |
| SCHEMBL2884597 | 0.67 | — | — | |
| SCHEMBL1851994 | 0.65 | — | — | |
| SCHEMBL10884969 | 0.65 | — | — | |
| SCHEMBL2179391 | 0.63 | — | — | |
| SCHEMBL8918830 | 0.63 | — | — | |
| SCHEMBL2002077 | 0.63 | — | — | |
| SCHEMBL2342739 | 0.63 | — | — | |
| SCHEMBL25358772 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964049-B | Transition metal compound, olefin polymerization catalyst composition containing same, preparation method and application | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-110964049-A | Transition metal compound, olefin polymerization catalyst composition containing same, preparation method and application | 万华化学集团股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-108084115-B | Preparation method of pramipexole dihydrochloride and intermediate thereof | 上海博志研新药物技术有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-1878731-B1 | Process for producing pramipexole | HELM AG (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1878731-A1 | Process for producing pramipexole | Helm AG (DE) | 2008-01-16 | — | — | EP | disclosed |