Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335014 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL11294913 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTLMNAHSD17B10HDAC1 | |
| SCHEMBL23381716 | 0.80 | ESR1 (0.51) | ALDH1A1KDM4EHTTHSD17B10CFTR | |
| Sulfuric Acid SCHEMBL11088013 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHTT | |
| SCHEMBL5623571 | 0.79 | POLB (0.54) | ALDH1A1KDM4EHTTLMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL4329941 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HTTLMNAHDAC1KMT2A | |
| SCHEMBL27244976 | 0.79 | POLB (0.54) | ALDH1A1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL20164184 | 0.79 | KDM4E (0.37) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL20164187 | 0.79 | KDM4E (0.37) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL6455051 | 0.78 | HDAC3 (0.57) | ALDH1A1KDM4EHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |