SCHEMBL4598442

SCHEMBL4598442

Cn1c(C#N)ccc1-c1ccc(OC(N)=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 15/20 0.62
AR P10275 6/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4423818 0.77 PGR (1.00) PGRAR
SCHEMBL3173849 0.76 AR (0.69) PGRAR
SCHEMBL4611824 0.74 PGR (0.56) PGRAR
SCHEMBL3175726 0.73 PGR (0.79) PGRAR
SCHEMBL3186982 0.73 PGR (1.00) PGRAR
SCHEMBL4421276 0.73 PGR (1.00) PGRAR
SCHEMBL4429185 0.73 PGR (1.00) PGRAR
SCHEMBL3012793 0.73 PGR (0.61) PGRAR
SCHEMBL5444795 0.71 PGR (1.00) PGRAR
SCHEMBL4598680 0.71 PGR (0.62) PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910284-A1 CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF Wyeth (US) 2008-04-16 EP claimed
WO-2007016211-A1 CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF WYETH (US) 2007-02-08 WO claimed
EP-1910284-A1 CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF Wyeth (US) 2008-04-16 EP disclosed
WO-2007016211-A1 CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF WYETH (US) 2007-02-08 WO disclosed