Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.60 |
| ▸ | CCR4 | P51679 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758664 | 0.85 | CCR5 (0.56) | CCR5CCR4KCNH2 | |
| SCHEMBL3758660 | 0.85 | CCR5 (0.56) | CCR5CCR4KCNH2 | |
| SCHEMBL4597898 | 0.84 | CCR5 (0.56) | CCR5CCR4 | |
| SCHEMBL3754248 | 0.82 | CCR5 (0.53) | CCR5CCR4KCNH2 | |
| SCHEMBL3754244 | 0.82 | CCR5 (0.53) | CCR5CCR4KCNH2 | |
| SCHEMBL4610331 | 0.78 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL5572517 | 0.78 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL5572519 | 0.78 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL4610329 | 0.78 | CCR5 (0.72) | CCR5CCR4KCNH2 | |
| SCHEMBL3764788 | 0.78 | CCR5 (0.60) | CCR5CCR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |