Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methyl Red. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.94 |
| ▸ | IDE | P14735 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 13/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 11/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Red SCHEMBL51823 | 0.97 | MYC (1.00) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Red SCHEMBL343366 | 0.97 | MYC (1.00) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Red SCHEMBL30182635 | 0.97 | MYC (1.00) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Red SCHEMBL28221553 | 0.95 | MYC (0.97) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Red SCHEMBL29837433 | 0.95 | MYC (0.97) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Yellow SCHEMBL9446361 | 0.86 | MYC (0.79) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Dimethyl Yellow SCHEMBL9446359 | 0.86 | MYC (0.79) | MYCIDEMAPTMAPK1L3MBTL1 | |
| SCHEMBL11511140 | 0.84 | MYC (0.76) | MYCIDEMAPTMAPK1L3MBTL1 | |
| SCHEMBL16983234 | 0.83 | MYC (0.74) | MYCIDEMAPTMAPK1L3MBTL1 | |
| Methyl Red SCHEMBL36580593 | 0.82 | MYC (0.74) | MYCIDEMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080223413-A1 | Color changing soap | MILLIKEN & COMPANY | 2008-09-18 | — | — | US | disclosed |
| WO-2008112073-A2 | COLOR CHANGING SOAP | MILLIKEN & COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |
| EP-1878756-A1 | Labeled tackifiers | National Starch and Chemical Investment Holding Corporation (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20080009573-A1 | Labeled tackifiers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORP. | 2008-01-10 | — | — | US | disclosed |