Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 2/20 | 0.42 |
| ▸ | GRM6 | O15303 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752273 | 0.78 | CYP1A2 (0.35) | CYP2C9ALDH1A1CYP1A2DPP4 | |
| SCHEMBL14015265 | 0.74 | KMT2A (0.42) | GRM4CYP2C19MEN1KMT2AGRM8 | |
| SCHEMBL9334836 | 0.68 | DPP4 (0.37) | ALDH1A1CYP1A2DPP4 | |
| SCHEMBL9334842 | 0.68 | DPP4 (0.37) | ALDH1A1CYP1A2DPP4 | |
| SCHEMBL10612524 | 0.67 | KMT2A (0.61) | KMT2AALDH1A1LMNA | |
| SCHEMBL15467216 | 0.67 | KMT2A (0.61) | KMT2AALDH1A1LMNA | |
| SCHEMBL14598558 | 0.65 | FFAR3 (0.33) | KMT2A | |
| SCHEMBL13319984 | 0.61 | GRM4 (1.00) | GRM4CYP2C19MEN1KMT2AGRM8 | |
| SCHEMBL12648585 | 0.61 | GRM4 (1.00) | GRM4CYP2C19MEN1KMT2AGRM8 | |
| SCHEMBL3954836 | 0.61 | GRM4 (1.00) | GRM4CYP2C19MEN1KMT2AGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138620-A2 | 1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACIDS DERIVATIVES | FAUST PHARMACEUTICALS (FR) | 2008-11-20 | — | — | WO | disclosed |