Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 7/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | GRM8 | O00222 | 2/20 | 1.00 |
| ▸ | GRM6 | O15303 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659587 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL3954836 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL8476727 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL659588 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL12648585 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL3328641 | 1.00 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1064244 | 0.79 | CYP1A2 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1063416 | 0.79 | CYP1A2 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL1263461 | 0.79 | CYP1A2 (1.00) | GRM4CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL15060220 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | RAMOT AT AVIV UNIVERSITY LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | RAMOT AT AVIV UNIVERSITY LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144868-A1 | Novel Neuroprotective Compounds and Uses Thereof | GRM2, GRIN1, GRM3 | GRM4 8/4885CYP1A2 2633/4885CYP2C19 1302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.