SCHEMBL4598639

SCHEMBL4598639

[CH2]C(=O)[C@H](C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337322 1.00
SCHEMBL272583 0.75
Alanine SCHEMBL20582916 0.74
Alanine SCHEMBL27461491 0.74
Alanine SCHEMBL11180815 0.74
Alanine SCHEMBL254290 0.72 SLC7A5 (0.59)
Alanine SCHEMBL452350 0.72 SLC7A5 (0.59)
Alanine SCHEMBL14764702 0.72 SLC7A5 (0.59)
D-Alanine SCHEMBL614024 0.72 SLC7A5 (0.59)
SCHEMBL12134091 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220214354-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2022-07-07 US disclosed
EP-3948297-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2022-02-09 EP disclosed
WO-2020201350-A1 MEANS AND METHODS FOR SINGLE MOLECULE PEPTIDE SEQUENCING VIB VZW (BE) 2020-10-08 WO disclosed
EP-1906971-A2 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2008-04-09 EP disclosed
US-20080076740-A1 Antiviral compounds GILEAD SCIENCES, INC. 2008-03-27 US disclosed
US-20070072855-A1 5-(5-Chloro-2,4-dihydroxy-phenyl)-4-(4-methoxy-phenyl)-2H-pyrazole-3-carboxylic acid, for example; for treatment of diseases which are mediated by excessive or inappropriate HSP90 activity, such as cancers VERNALIS (CAMBRIDGE) LIMITED (GB) 2007-03-29 US disclosed
WO-2007014352-A2 ANTIVIRAL PHOSPHONATE CONJUGATES FOR INHIBITION OF HIV GILEAD SCIENCES, INC. (US) 2007-02-01 WO disclosed
US-4760180-A N-terminally substituted dipeptide amides G. D. SEARLE & CO. (US) 1988-07-26 US disclosed
EP-0213481-A2 N-terminally substituted dipeptide amides No. 2 G.D. Searle & Co. (US) 1987-03-11 EP disclosed